2,845 research outputs found

    Effect of stripe order strength for the Nernst effect in La_{2-x}Sr_xCu_4 single crystals

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    We have precisely measured the Nernst effect in Nd-doped La2−x_{2-x}Srx_xCuO4_4 single crystals with controlling the strength (stability) of the stripe order. We found that the onset temperature TonsetT_{onset}, where the Nernst signal starts increasing, does not change conspicuously in spite of Nd-doping. At low temperatures, on the other hand, the absolute value of the Nernst signal is strongly suppressed in accordance with the strength of the stripe order. These results imply that the fluctuation of (charge) stripe order enhances the Nernst signal below TonsetT_{onset} at high temperatures, and then the stripe order enhanced by Nd-doping suppresses the superconducting fluctuation to reduce the Nernst signal at low temperatures. We also observed an increase of the Nernst signal below the charge order temperature TchT_{ch} which is observed in diffraction measurement.Comment: 3pages, 2figure

    Levi problem and semistable quotients

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    A complex space XX is in class QG{\mathcal Q}_G if it is a semistable quotient of the complement to an analytic subset of a Stein manifold by a holomorphic action of a reductive complex Lie group GG. It is shown that every pseudoconvex unramified domain over XX is also in QG{\mathcal Q}_G.Comment: Version 2 - minor edits; 8 page

    Polarised epithelial monolayers of the gastric mucosa reveal insights into mucosal homeostasis and defence against infection

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    Objective Helicobacter pylori causes life-long colonisation of the gastric mucosa, leading to chronic inflammation with increased risk of gastric cancer. Research on the pathogenesis of this infection would strongly benefit from an authentic human in vitro model. Design Antrum-derived gastric glands from surgery specimens served to establish polarised epithelial monolayers via a transient air–liquid interface culture stage to study cross-talk with H. pylori and the adjacent stroma. Results The resulting ‘mucosoid cultures’, so named because they recapitulate key characteristics of the gastric mucosa, represent normal stem cell-driven cultures that can be passaged for months. These highly polarised columnar epithelial layers encompass the various gastric antral cell types and secrete mucus at the apical surface. By default, they differentiate towards a foveolar, MUC5AC-producing phenotype, whereas Wnt signalling stimulates proliferation of MUC6-producing cells and preserves stemness—reminiscent of the gland base. Stromal cells from the lamina propria secrete Wnt inhibitors, antagonising stem-cell niche signalling and inducing differentiation. On infection with H. pylori, a strong inflammatory response is induced preferentially in the undifferentiated basal cell phenotype. Infection of cultures for several weeks produces foci of viable bacteria and a persistent inflammatory condition, while the secreted mucus establishes a barrier that only few bacteria manage to overcome. Conclusion Gastric mucosoid cultures faithfully reproduce the features of normal human gastric epithelium, enabling new approaches for investigating the interaction of H. pylori with the epithelial surface and the cross-talk with the basolateral stromal compartment. Our observations provide striking insights in the regulatory circuits of inflammation and defence.</p

    Pseudoconvex domains spread over complex homogeneous manifolds

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    Using the concept of inner integral curves defined by Hirschowitz we generalize a recent result by Kim, Levenberg and Yamaguchi concerning the obstruction of a pseudoconvex domain spread over a complex homogeneous manifold to be Stein. This is then applied to study the holomorphic reduction of pseudoconvex complex homogeneous manifolds X=G/H. Under the assumption that G is solvable or reductive we prove that X is the total space of a G-equivariant holomorphic fiber bundle over a Stein manifold such that all holomorphic functions on the fiber are constant.Comment: 21 page

    Development of geothermal field following the 2000 eruption of Usu volcano as revealed by ground temperature, resistivity and self-potential variations

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    The 2000 eruption of Usu volcano, NE Japan, took place on the foot of the somma, and formed a cryptodome of 65 m high accompanying numerous faults. We made repeated measurements of ground temperature, Self-Potential (SP) and electrical resistivity, in order to clarify the mechanism of development of the newly formed geothermal field on the fault zone. Prior to the expansion of the geothermal field, we detected a resistive zone at the center of the geothermal zone and it supposed to evidence that the zone involving dry steam phase had been formed beneath the fault zone. A rapid expansion of the geothermal field followed along the fault zone away from the craters. The place of maximum amplitude of the SP field also migrated following the expansion of the high ground temperature zone. The high resistive part has shrunk as a consequence of the progress of condensation to warm the surroundings. Based on the observations, we delineated the process of the hydrothermal circulation. Considering the topographic effect of the SP field observed on the highly permeable zone in the Usu somma, the potential flow along the slope of the soma was expected to play an important role to promote the rapid expansion of the geothermal field and the migration of the most active part

    Lung adenocarcinoma with giant cyst formation showing a variety of histologic patterns: a case report

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    <p>Abstract</p> <p>Introduction</p> <p>Lung cancer with large cyst formation is relatively rare. This is a case report of a patient with lung cystic adenocarcinoma with multiple histologic patterns. This type of lung adenocarcinoma is believed to be the first reported case in English language medical literature.</p> <p>Case presentation</p> <p>A 60-year-old Japanese woman was admitted to hospital complaining of dyspnea and died of respiratory failure. She had been suffering from lung cancer with pleural effusion for five years. Autopsy analysis revealed lung adenocarcinoma with large cyst formation showing a variety of histologic patterns.</p> <p>Conclusions</p> <p>Autopsy analysis of this atypical case of lung cancer may provide insight and lead to a better understanding of the heterogeneity and clonal expansion of lung adenocarcinoma.</p

    Implementation of higher-order absorbing boundary conditions for the Einstein equations

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    We present an implementation of absorbing boundary conditions for the Einstein equations based on the recent work of Buchman and Sarbach. In this paper, we assume that spacetime may be linearized about Minkowski space close to the outer boundary, which is taken to be a coordinate sphere. We reformulate the boundary conditions as conditions on the gauge-invariant Regge-Wheeler-Zerilli scalars. Higher-order radial derivatives are eliminated by rewriting the boundary conditions as a system of ODEs for a set of auxiliary variables intrinsic to the boundary. From these we construct boundary data for a set of well-posed constraint-preserving boundary conditions for the Einstein equations in a first-order generalized harmonic formulation. This construction has direct applications to outer boundary conditions in simulations of isolated systems (e.g., binary black holes) as well as to the problem of Cauchy-perturbative matching. As a test problem for our numerical implementation, we consider linearized multipolar gravitational waves in TT gauge, with angular momentum numbers l=2 (Teukolsky waves), 3 and 4. We demonstrate that the perfectly absorbing boundary condition B_L of order L=l yields no spurious reflections to linear order in perturbation theory. This is in contrast to the lower-order absorbing boundary conditions B_L with L<l, which include the widely used freezing-Psi_0 boundary condition that imposes the vanishing of the Newman-Penrose scalar Psi_0.Comment: 25 pages, 9 figures. Minor clarifications. Final version to appear in Class. Quantum Grav
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